True or False: In CPB practice, temperature is the only determinant of cerebral blood flow.

The assertion that temperature is the only determinant of cerebral blood flow is false. While temperature does play a significant role in influencing cerebral blood flow, it is not the sole factor. Cerebral blood flow is affected by a multitude of factors including systemic blood pressure, blood viscosity, the concentration of carbon dioxide in the blood (hypercapnia can lead to vasodilation and increased blood flow), and the regulation of cerebral perfusion pressure.

In clinical practice, particularly during cardiopulmonary bypass (CPB), the management of temperature is crucial as hypothermia can reduce metabolic demands and protect the brain. However, the overall cerebral perfusion is regulated by complex physiological responses to changing conditions in the body, indicating that temperature is just one component of a broader system that ensures adequate cerebral blood supply.

Thus, the correct response recognizes that temperature is not the only determinant. Instead, it is part of a network of physiological signals that collectively maintain cerebral perfusion.