Wetting of the membrane module in an oxygenator is considered:

Wetting of the membrane module in an oxygenator refers to the phenomenon where the hydrophilic properties of the membrane material allow blood or plasma components to penetrate or adhere to its surface. This results in plasma leakage, which can lead to several complications during cardiopulmonary bypass. The presence of wetting indicates that the membrane is saturated with fluid, which can affect the efficiency of gas exchange, increase the risk of thrombosis, and result in the loss of blood components.

Plasma leakage occurs when the membrane is compromised or when its wetting characteristics change, potentially leading to an influx of plasma or other blood elements into areas that would normally be gas exchange chambers. In the context of oxygenators, this is critical, as it can impair their function and ultimately influence patient outcomes during surgery.

Understanding this process is essential for healthcare professionals working with cardiovascular perfusion, as it emphasizes the importance of maintaining the integrity and function of oxygenators throughout surgical procedures.